关键词: 帕金森病, 静止性震颤, 外周神经, 电刺激, 单片机, 连续可调节, 方波, 稳定性

Abstract:

In view of the pathogenesis and mechanism of upper limb quiescent tremor in patients with Parkinson's disease and analyzing the commonly used clinical therapeutic parameters, a peripheral electrical nerve stimulator system is designed to effectively inhibit upper limb quiescent tremor in patients with Parkinson's disease. This system uses STM32F103C8T6 as the core of the hardware system design. The charging circuit, the boost circuit, the pulse modulation circuit, the analog switch circuit and the serial port touch screen module are communicatied with the main control, and RT-Thread is used to write a single chip computer program to realize the intelligent control of the above modules. Parameters of the touch screen are set to generate square wave electrical stimulation pulses that can be continuously adjusted in amplitude, frequency, pulse width and time to accurately stimulate the median nerve and radial nerve.The experimental results show that the proposed method has a good stability, the system can generate a predetermined intensity of electrical stimulation signal, maintain a good performance of constant pressure, and provide support for static tremor electrical stimulation treatment.

Key words: Parkinson's disease, static tremor, peripheral nerve, electrical stimulation, single chip microcomputer, continuously adjustable, square wave, stability