静息态下汉字视觉加工脑网络的有效连接度研究

doi:10.3969/j.issn.1001-2400.2011.06.010

J4 ›› 2011, Vol. 38 ›› Issue (6): 62-67.doi: 10.3969/j.issn.1001-2400.2011.06.010

静息态下汉字视觉加工脑网络的有效连接度研究

赵继政;赵恒;李军

(西安电子科技大学生命科学技术学院，陕西西安 710071)

收稿日期:2010-09-04 出版日期:2011-12-20 发布日期:2011-11-29
通讯作者: 赵继政
基金资助:
中科院百人计划资助项目;国家自然科学基金资助项目(30970774,60901064,30873462,30870685,81000641,81000640,81071217,31028010);中国科学院知识创新工程重要方向资助项目(KGCX2-YW-129);国家重点基础研究发展计划(973计划)资助项目(2006CB705700);863计划资助项目(2008AA01Z411);中央高校基本科研业务费专项资助项目

Effective connectivity of the Chinese character visual-processing network: a resting state research

ZHAO Jizheng;ZHAO Heng;LI Jun

(School of Life Sciences and Technology, Xidian Univ., Xi'an 710071， China)

Received:2010-09-04 Online:2011-12-20 Published:2011-11-29
Contact: ZHAO Jizheng
Supported by:
赵继政(1982-)，男，西安电子科技大学博士研究生，E-mail: zhaojizheng@life.xidian.edu.cn

摘要/Abstract

摘要：

为了分析负责汉字视觉加工的左侧枕下回、左侧梭状回中部、左侧顶上小叶和左侧额中回在静息状态时的信息交互模式，采用多变量Granger因果模型对这些脑区在静息状态的时间序列进行分析．该方法可以有效地避免因为变量具有公共输入而导致的“伪”因果关系．研究结果表明，在静息态下，左侧枕下回和左侧梭状回中部都与左侧顶上小叶存在显著的双向Granger因果连接;左侧枕下回对左侧额中回、左侧额中回对左侧梭状回中部均具有显著的Granger因果影响．上述结果反映了汉字视觉加工脑区在没有外界刺激条件下也存在着动态的信息交互，从而肯定了静息态下存在一个处于准备状态的汉字视觉加工脑网络．

关键词: 磁共振成像, 汉字加工, 静息态, Granger因果模型, 连接度

Abstract:

Neuroimaging studies have revealed that several brain regions play an important role in the visual processing of Chinese characters, including the left parts of inferior occipital gyrus, middle fusiform gyrus, superior parietal lobule, and middle frontal gyrus. In order to investigate the intercommunicating pattern among these brain regions in the resting state, the method of the multivariate Granger Causality Model (GCM) is employed to analyze the time series of these brain regions, which could provide robustness to false causality in case of variables with a common source. The results demonstrate that there are significantly bidirectional Granger causality connections between the left inferior occipital gyrus and superior parietal lobule, as well as between the left middle fusiform gyrus and superior parietal lobule; the left inferior occipital gyrus Granger-causes the left middle frontal gyrus; the left middle fusiform gyrus is Granger-caused by the left middle frontal gyrus. All the results above reveal the intercommunications among the brain regions which respond to the visual processing of Chinese characters without any explicit tasks, and indicate a preparatory brain networks for the highly probable character input in the resting state.

Key words: magnetic resonance imaging, Chinese character processing, resting state, granger causality model, connectivity

中图分类号:

TP319.4

赵继政;赵恒;李军. 静息态下汉字视觉加工脑网络的有效连接度研究[J]. J4, 2011, 38(6): 62-67.

ZHAO Jizheng;ZHAO Heng;LI Jun. Effective connectivity of the Chinese character visual-processing network: a resting state research[J]. J4, 2011, 38(6): 62-67.

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静息态下汉字视觉加工脑网络的有效连接度研究

Effective connectivity of the Chinese character visual-processing network: a resting state research

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