With multiple interferers on both the relays and the destination,three opportunistic relaying protocols are proposed to minimize the outage probability in distinct cases:with direct transmission negligible,selection combining (SC) deployed at the destination,and maximum ratio combining (MRC) deployed at the destination.The exact outage probabilities of opportunistic relaying protocols are derived over independent identically distributed and independent non-identically distributed Rayleigh fading channels.Finally,simulation results validate our analysis and show that,in terms of outage probability,when the channels between the source and the relays are in deep fading,the opportunistic relaying protocol with SC is better than the other two protocols. Conversely,the opportunistic relaying protocol with MRC is the best.