Journal of Xidian University ›› 2016, Vol. 43 ›› Issue (4): 184-190.doi: 10.3969/j.issn.1001-2400.2016.04.032

• Article • Previous Articles     Next Articles

Neurofilament protein automatic tracking of the  particle filter algorithm based on multiple methods fusion

JU Gang;YUAN Liang;LIU Xiaoyue   

  1. (School of Mechanical Engineering, Xinjiang University, Urumqi  830047, China)
  • Received:2015-08-28 Online:2016-08-20 Published:2016-10-12

Abstract:

The neurofilament protein serves as the marker of the state for ALS (Amyotrophic Lateral Sclerosis) in the medical filed. In order to accurately capture the motion characteristics of the neurofilament protein in the axon, a new-type algorithm based on the particle filtering of multiple methods-fusion is introduced in this paper. This fusion algorithm integrates the advantages of the color histogram, kernel function method, and graph model strength into the particle filtering algorithm. In addition, in order to solve the problem of sample impoverishment, which will lead to the majority of particles overlapping on one single point in the computation of the particle filter, the re-sampling method is utilitied. However, the re-sampling method easily causes the loss of the particle anisotropy, which will reduce the tracking precision or even fail to the track. We present a new re-sampling constrained method to improve the particle anisotropy in the particle filtering. Experimental results indicate that the algorithm based on the improved method of re-sampling and the particle filter of multiple methods-fusion can effectively reduce the number of overlapping particles and precisely track the deformed neurofilament protein. Such a tracking method will be helpful in the research on the neurofilament protein in the medical filed.

Key words: target tracking, importance sampling, multiple methods-fusion, neurofilament protein, particle filtering, re-sampling constraints