血糖近红外定量分析方法研究

doi:10.16180/j.cnki.issn1007-7820.2020.02.009

Abstract

Abstract:

In order to solve the problem of traditional invasive blood glucose detection, the noninvasive blood glucose detection technology by near infrared spectroscopy was studied. The near infrared spectra of glucose solution were measured by TALYS ASP531 near infrared spectrometer of ABB Company. The selected modeling band was 5500~6500 cm ^-1 and the calibration model between spectral data and corresponding concentration was established by partial least squares method. According to the experimental results, the determination coefficient of the calibration model reached 0.98399, the root mean square deviation was 1.023 26 mmol·L ^-1, and the error distribution was -1.3~1.7 mmol·L ^-1. The results demonstrated the feasibility of non-invasive detection of human blood glucose concentration by near-infrared, and provided a reliable basis for the study of near-infrared blood glucose detection.

Key words: blood glucose, NIR, noninvasive, glucose solution, PLS, PCR

CLC Number:

TN219

HU Jie,WANG Kai,WANG Yagang,LI Wenshuai. Study on Near-infrared Quantitative Analysis of Blood Glucose[J].Electronic Science and Technology, 2020, 33(2): 48-53.

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	偏最小二乘法	主成分回归
决定系数	0.983 99	0.971 64
校正均方差	1.023 26	1.365 97
误差范围	-1.3~1.7 mmol·L^-1	-3~2.4 mmol·L^-1
主因子数	6	6

Study on Near-infrared Quantitative Analysis of Blood Glucose

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