Electronic Science and Technology ›› 2020, Vol. 33 ›› Issue (2): 48-53.doi: 10.16180/j.cnki.issn1007-7820.2020.02.009

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Study on Near-infrared Quantitative Analysis of Blood Glucose

HU Jie1,WANG Kai2,WANG Yagang1,LI Wenshuai3   

  1. 1. School of Optical-Electrical and Computer Engineering,University of Shanghai for Science and Technology
    2. Printing Equipment Engineering,Shanghai Publishing and Printing College,Shanghai 200093,China
    3. Hangzhou Huixin Medical Technology Co., Ltd, Hangzhou 310006,China
  • Received:2019-01-13 Online:2020-02-15 Published:2020-03-12
  • Supported by:
    National Natural Science Foundation of China(61074087)


In order to solve the problem of traditional invasive blood glucose detection, the noninvasive blood glucose detection technology by near infrared spectroscopy was studied. The near infrared spectra of glucose solution were measured by TALYS ASP531 near infrared spectrometer of ABB Company. The selected modeling band was 5500~6500 cm -1 and the calibration model between spectral data and corresponding concentration was established by partial least squares method. According to the experimental results, the determination coefficient of the calibration model reached 0.98399, the root mean square deviation was 1.023 26 mmol·L -1, and the error distribution was -1.3~1.7 mmol·L -1. The results demonstrated the feasibility of non-invasive detection of human blood glucose concentration by near-infrared, and provided a reliable basis for the study of near-infrared blood glucose detection.

Key words: blood glucose, NIR, noninvasive, glucose solution, PLS, PCR

CLC Number: 

  • TN219